Archive for March 2011

Deep Brain Stimulation for Parkinsons’s Disease

University of Chicago Journal Club, March 2011

Editor, B Roitberg, MD


Warnke P
Hekmat-Panah J
Roitberg B

Khader-Eliyas J
Bhansali A
Dey M
Hsieh J

Article 1:

Williams A, Gill S, Varma T, Jenkinson C, Quinn N, Mitchell R, Scott R, Ives N, Rick C, Daniels J, Patel S, Wheatley K; PD SURG Collaborative Group. Deep brain stimulation plus best medical therapy versus best medical therapy alone for advanced Parkinson’s disease (PD SURG trial): a randomised, open-label trial. Lancet Neurol. 2010 Jun;9(6):581-91.


The PD SURG trial we are discussing today is an open label randomized ‘intent to treat’ trial comparing medical treatment alone with combined medical and surgical treatment. The trial was conducted across 13 neurosurgical centers in the UK from 2000 to 2006. The investigators intended to prove the usefulness of deep brain stimulation in treating Parkinson’s patients by showing a 10-point difference between both groups on PDQ 39 (Parkinson’s disease Questionnaire). Secondary endpoints included changes in UPDRS (Unified Parkinsons Disease Rating Scale) and DRS II (Dementia Rating Scale II) at the end of 1 year following treatment. This article presents the follow up data at 1 year.

Continue reading ‘Deep Brain Stimulation for Parkinsons’s Disease’ »

Sympathy and help for those in the Middle East/Asia

On behalf of the Board of Surgical Neurology International and its readers world wide, I offer our sympathy to the people in Algeria, Tunisia, Egypt, Yemen, Jordan, Saudi Arabia, and China in your recent struggles for individual liberty and freedom. We also understand that there are food shortages and high prices which makes everyone’s life difficult.

If there is anything we can do as a worldwide community of neurosurgeons. please ask in the comment section below this note. We will try our best to help you in any way we can.

James I. Ausman, MD, PhD
Editor in Chief

Help for our friends and colleagues in Japan

On behalf of the Board of Surgical Neurology International and its readers world wide, I offer our sincere concern for the people of Japan in its recent natural devastation. If there are specific things or people that are needed or that we can supply as a neurosurgical community, please use the comment section after this note to ask the world wide community for your needs. We will do our best to fulfill them.

James I. Ausman, MD, Phd

How I Do It: Blood-blister like aneurysm of the supraclinoid internal carotid artery

Stereotactic Resection, Right Thalamic Pilocytic Astrocytoma

Giant Partially-Thrombosed Aneurysm